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. 2020 Oct 27;10:18348. doi: 10.1038/s41598-020-75340-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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KEGG pathway enrichment analysis of the host response towards vvIBDV infection. These KEGG pathways were generated using DE genes from IEL-NK cells obtained from RNA-Seq. (a) Cytokine-cytokine receptor interaction pathway. (b) Toll-like receptor signalling pathway. (c) Apoptosis pathway. The down-regulated DE genes are highlighted in blue and up-regulated DE genes are highlighted in red. Pathways were adopted from KEGG pathway database⁵⁹. The green and white coloured boxes are default colours generated by the software, depicting genes that were not the DE on RNA-Seq, and unidentified genes in the organism-specific pathway, respectively.

KEGG pathway enrichment analysis of the host response towards vvIBDV infection. These KEGG pathways were generated using DE genes from IEL-NK cells obtained from RNA-Seq. (a) Cytokine-cytokine receptor interaction pathway. (b) Toll-like receptor signalling pathway. (c) Apoptosis pathway. The down-regulated DE genes are highlighted in blue and up-regulated DE genes are highlighted in red. Pathways were adopted from KEGG pathway database⁵⁹. The green and white coloured boxes are default colours generated by the software, depicting genes that were not the DE on RNA-Seq, and unidentified genes in the organism-specific pathway, respectively.