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. 2020 Oct 27;10:18332. doi: 10.1038/s41598-020-75428-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Manhattan analysis and candidate genes exploration. A-B: Manhattan plot representing F_st values for each SNP across Chromosomes for two subpopulations of altitude and geography. The genomic region with significant F_st values were highlighted in arrows. C: Venn diagram representing overlapped SNPs for two subpopulations of altitude and geography. D: Numbers of corresponding genes harboring overlapped SNPs for two subpopulations of altitude and geography. E: overlapped genes with 1% top values between F_st and ZHp.