Table 2.
Protective effects of melatonin on aluminum chloride (AlCl3-) induced alternation in the liver and kidney markers in serum of rats.
| Parameter | CON | MEL | AlCl3 | MEL+AlCl3 |
|---|---|---|---|---|
| ALT (U/l) | 59.31 ± 3.1 | 57.56 ± 4.93 | 87.65 ± 8.75a | 61.87 ± .5.51b |
| AST (U/l) | 47.78 ± 2.77 | 45.76 ± 3.65 | 76.54 ± 6.57a | 55.36 ± 3.63b |
| Bilirubin (mg%) | 0.98 ± 0.05 | 0.87 ± 0.07 | 1.9 ± 0.75a | 1.1 ± 0.64b |
| Urea (mg%) | 43.81 ± 8.54 | 45.58 ± 7.9 | 76.53 ± 9.65a | 57.42 ± 7.58ab |
| Creatinine (mg%) | 0.55 ± 0.09 | 0.61 ± 0.03 | 3.2 ± 0.73a | 1.46 ± 0.46ab |
Data are expressed as mean ± SD values (n = 7). ap < 0.05 vs. the control group; bp < 0.05 vs. the AlCl3-intoxicated group, using Tukey's post hoc test.