Table 2.
Diseases ameliorated by LC.
| Disease | Drug | Dosage (mg/kg) | Model | Ref |
|---|---|---|---|---|
| Atherosclerosis | Total lactone | 30, 60 | ApoE−/− mice | [56] |
| Cerebral trauma | Ligustrazine | 20 | Controlled cortical impact mice | [49] |
| Migraine | Senkyunolide I | 16, 32 | Nitroglycerin-treated rats | [58] |
| Diabetic nephropathy | Ethanol extraction | 25, 50, 100 | Streptozotocin-treated mice | [24] |
| Intervertebral disc degeneration | Ligustilide | 10 | Mice treated by surgery | [42] |
| Oxidative damage on renal | Ligustrazine | 80 | Gentamicin-treated mice | [59] |
| Ischemic cerebral stroke | Senkyunolide I | 36, 72 | Ischemia-reperfusion injured rats | [53] |
| Cognitive impairment | Ligustilide | — | D-galactose-treated mice | [60] |