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. 2020 Oct 19;2020:8205983. doi: 10.1155/2020/8205983

Table 2.

Diseases ameliorated by LC.

Disease Drug Dosage (mg/kg) Model Ref
Atherosclerosis Total lactone 30, 60 ApoE−/− mice [56]
Cerebral trauma Ligustrazine 20 Controlled cortical impact mice [49]
Migraine Senkyunolide I 16, 32 Nitroglycerin-treated rats [58]
Diabetic nephropathy Ethanol extraction 25, 50, 100 Streptozotocin-treated mice [24]
Intervertebral disc degeneration Ligustilide 10 Mice treated by surgery [42]
Oxidative damage on renal Ligustrazine 80 Gentamicin-treated mice [59]
Ischemic cerebral stroke Senkyunolide I 36, 72 Ischemia-reperfusion injured rats [53]
Cognitive impairment Ligustilide D-galactose-treated mice [60]