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Hsa_circ_0039053 sponged miR-637 in HCC. (A, B) Schematic representation of the miR-637 site in hsa_circ_0039053. (C) Hsa_circ_0039053 knockdown increased miR-637 expression in HCC cells. (D) Luciferase activity in HCC cells co-transfected with miR-637 mimics and luciferase reporters containing mutant or wild-type hsa_circ_0039053. (E, F) RIP assay revealed that hsa_circ_0039053 and miR-637 were enriched in the Ago2 platform. *P < 0.05.
