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. 2020 Oct 8;11(23):6950–6959. doi: 10.7150/jca.48998

Figure 8.

Figure 8

Hsa_circ_0039053 elevated USP21 expression via sponging miR-637. (A-C) Spearman's correlation coefficient was carried out to analyze the linear correlation among hsa_circ_0039053, miR-637, and USP21 in HCC tissues. (D) MiR-637 inhibitors abolished the impacts of hsa_circ_0039053 inhibition on USP21 expression in HCC cells. (E-H) SP21 overexpression (miR-637 inhibition) abolished the roles of hsa_circ_0039053 silencing on HCC cells proliferation and invasion abilities. (I) A schematic diagram of the hsa_circ_0039053/miR-637/USP21 axis in HCC progression. *P < 0.05.