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. 2020 Oct 17;11(23):7009–7022. doi: 10.7150/jca.47895

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RRM2 co-expression genes in LUAD (LinkedOmics). (A) The global RRM2 highly correlated genes identified by the Pearson test in LUAD. Red and green dots represent positively and negatively significantly correlated genes with RRM2, respectively. (B and C) Heatmaps showing the top 50 genes positively and negatively correlated with RRM2 in LUAD. (D and E) Significantly enriched GO: Biological process annotations and KEGG pathways of RRM2 in LUAD. (F and G) Survival heatmaps of the top 50 genes positively and negatively correlated with RRM2 in LUAD. The survival heatmaps show the hazard ratios in the logarithmic scale (log10) for different genes. The red and blue blocks denote higher and lower risks, respectively. The rectangles with frames mean the significant unfavorable and favorable results in prognostic analyses (p-value < 0.05). FDR: false discovery rate; KEGG: Kyoto Encyclopedia of Genes and Genomes; GO: Gene Ontology; LUAD: Lung adenocarcinoma.