Figure 3. Risk of the Primary Outcome (NACE) at 1 Year.

Net adverse clinical events comprise ischemic events (recurrent acute myocardial infarction, revascularization, or ischemic stroke) and hemorrhagic events (hemorrhagic stroke or gastrointestinal bleeding) in propensity score-matched cohorts from each data source. The summary hazard ratios were calculated using a random-effects model. A hazard ratio greater than 1 indicates higher risk in the ticagrelor group. The size of the data marker indicates the weight of the study. Error bars indicate 95% CIs.