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. 2020 Aug 12;123(9):1437–1444. doi: 10.1038/s41416-020-1024-2

Table 2.

Concordance of dEGFR39 for EGFR mutations in FFPE tissues as compared to ARMS.

Mutant type Patient count PPA
(95% CI)
NPA
(95% CI)
OPA
(95% CI)
TP FN TN FP
L858R/L861Q 15 0 14 1

100

79.61–100%

93.33

70.18–98.81%

96.67

83.33–99.41%

S768I 8 0 19 3

100

67.56–100%

86.36

66.66–95.25%

90

74.38–96.54%

G719X 1 0 29 0

100

20.65–100%

100

88.30–100%

100

88.65–100%

19Del 2 0 28 0

100

34.24–100%

100

87.94–100%

100

88.65–100%

20ins 5 1 19 5

83.33

43.65–96.99%

79.17

59.53–90.76%

80.00

62.69–90.50%

T790M 1 0 26 3

100

20.65–100%

89.66

73.61–96.42%

90

74.38–96.54%

Overall 17 1 3 9

94.44

74.24–99.01%

25

8.89–53.23%

66.67

48.78–80.77%

TP true positive, FN false negative, TN true negative, FP false positive, PPA positive predict agreement, NPA negative predict agreement, OPA overall predict agreement, CI confidence interval.