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RUNX1 overexpression blunts HSV-1 viral gene transcription over time. After Emp, R1, and R3 cell lines were infected with HSV-1 at an MOI of 1, the mRNA expression of immediate early genes (A), early genes (B), and late genes (C) was measured by RT-qPCR and normalized to HPRT mRNA at 12, 24, 48, and 72 hpi. The data are means ± the SE (n = 3). ##, P < 0.1; *****, P < 0.0001 (as assessed by two-way ANOVA tests).
