FIG 5.

Uninfected monocytes rapidly undergo caspase-dependent apoptosis. Human peripheral blood monocytes were mock or HCMV infected for 24 h, followed by treatment with 5 μM Z-VAD-FMK or vehicle control for an additional 24 h. Viability was measured by flow cytometry using PI and annexin staining. Results are representative of at least 3 independent experiments using different blood donors.