TABLE 4.
Percentage of occupancy for engineered N-glycan at position 632, determined by mass spectrometry
| Design | % Aglycosylation | Endo F efficiency (%) |
|---|---|---|
| Y632NS | 51 | 96 |
| ΔHVR1-Y632NS | 44 | 97 |
| Triplea | 22 | 100 |
a
Combination of ΔHVR1, H445P, and Y632NS.
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