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. 2020 Oct 28;15:133. doi: 10.1186/s13000-020-01048-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Knockdown of circ_0001421 inhibited cell growth of LC cells in vivo. a The expression of circ_0001421 was detected by qRT-PCR in A549 cells. b-c The tumor volume and weight in the groups of sh-NC and sh-circ_0001421 were shown. d-e The expression levels of circ_0001421 and miR-4677-3p in that tumor were measured by qRT-PCR. f The protein of CDCA3 was examined by western blot. *P < 0.05