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Characteristics of serum exosomal miR-5684 and miR-125b-5p. (A) Expression levels of miR-5684 and miR-125b-5p from serum exosomes (EXO) and exosome-depleted supernatant (EDS). (B) Expression levels of both miRNAs in exosomes treated with RNase A or in isolated RNA. (C, D) Expression levels of the miRNAs in exosomes incubated at room temperature for different durations (**P < 0.01, ****P < 0.0001, ns, not significant).
