Table 1.
Baseline characteristics of subjects
| TyG-BMI | P value | ||||
|---|---|---|---|---|---|
| Q1 (114.23–157.67) | Q2 (157.68–172.11) | Q3 (172.11–188.07) | Q4 (188.08–230.41) | ||
| N | 2442 | 2441 | 2442 | 2442 | |
| Age, years | 41.28 ± 14.48 | 41.71 ± 14.19 | 43.20 ± 15.01 | 43.66 ± 15.03 | < 0.001 |
| Sex | < 0.001 | ||||
| Women | 1243 (50.90%) | 1264 (51.78%) | 1185 (48.53%) | 1053 (43.12%) | |
| Men | 1199 (49.10%) | 1177 (48.22%) | 1257 (51.47%) | 1389 (56.88%) | |
| BMI, kg/m2 | 18.56 ± 1.10 | 20.31 ± 0.87 | 21.75 ± 0.88 | 23.49 ± 0.89 | < 0.001 |
| ALP, U/L | 64.16 ± 19.48 | 67.33 ± 23.42 | 70.88 ± 22.89 | 75.39 ± 22.12 | < 0.001 |
| GGT, U/L | 17.00 (14.00–21.00) | 17.00 (14.00–22.00) | 20.00 (16.00–26.00) | 24.00 (19.00–35.00) | < 0.001 |
| ALT, U/L | 13.00 (10.00–17.00) | 14.00 (11.00–18.00) | 15.00 (12.00–21.00) | 19.00 (14.00–25.00) | < 0.001 |
| AST, U/L | 19.00 (17.00–22.00) | 20.00 (17.00–23.00) | 21.00 (18.00–25.00) | 22.00 (19.00–26.00) | < 0.001 |
| TB, μmol/L | 12.22 ± 4.98 | 11.89 ± 4.71 | 12.18 ± 5.01 | 12.46 ± 4.97 | 0.012 |
| GLB, g/L | 29.35 ± 3.62 | 29.48 ± 3.73 | 29.53 ± 4.06 | 29.64 ± 4.05 | 0.104 |
| ALB, g/L | 44.48 ± 2.64 | 44.36 ± 2.75 | 44.21 ± 2.83 | 44.30 ± 2.78 | 0.009 |
| TP, g/L | 73.78 ± 3.97 | 73.77 ± 4.09 | 73.69 ± 4.19 | 73.89 ± 4.16 | 0.455 |
| Cr, mmol/L | 70.16 ± 21.11 | 73.21 ± 17.26 | 78.70 ± 26.06 | 86.05 ± 31.73 | < 0.001 |
| UA, μmol/L | 233.34 ± 69.44 | 248.48 ± 72.94 | 270.44 ± 78.98 | 302.16 ± 80.37 | < 0.001 |
| LDL-C, mmol/L | 1.97 ± 0.39 | 2.08 ± 0.40 | 2.16 ± 0.41 | 2.26 ± 0.41 | < 0.001 |
| HDL-C, mmol/L | 1.61 ± 0.32 | 1.55 ± 0.29 | 1.49 ± 0.28 | 1.41 ± 0.26 | < 0.001 |
| TG, mmol/L | 0.76 ± 0.23 | 0.90 ± 0.27 | 1.01 ± 0.28 | 1.20 ± 0.27 | < 0.001 |
| TC, mmol/L | 4.23 ± 0.54 | 4.31 ± 0.53 | 4.37 ± 0.52 | 4.45 ± 0.50 | < 0.001 |
| FPG, mmol/L | 4.85 ± 0.41 | 4.97 ± 0.45 | 5.09 ± 0.59 | 5.38 ± 1.04 | < 0.001 |
| SBP, mmHg | 111.13 ± 13.65 | 114.95 ± 14.27 | 119.68 ± 15.66 | 126.49 ± 16.40 | < 0.001 |
| DBP, mmHg | 67.74 ± 8.64 | 69.64 ± 9.31 | 72.09 ± 9.76 | 75.71 ± 10.22 | < 0.001 |
| Time, days | 1036.08 ± 398.69 | 1012.46 ± 401.00 | 995.29 ± 394.25 | 925.52 ± 399.07 | < 0.001 |
| TyG | 7.94 ± 0.31 | 8.13 ± 0.31 | 8.28 ± 0.30 | 8.50 ± 0.28 | < 0.001 |
| BUN, mmol/L | 4.29 ± 1.36 | 4.42 ± 1.31 | 4.55 ± 1.36 | 4.74 ± 1.43 | < 0.001 |
| DBIL, μmol/L | 2.46 ± 1.21 | 2.41 ± 1.28 | 2.39 ± 1.29 | 2.35 ± 1.17 | 0.136 |
| NAFLD | < 0.001 | ||||
| No | 2435 (99.71%) | 2406 (98.57%) | 2257 (92.42%) | 1828 (74.86%) | |
| Yes | 7 (0.29%) | 35 (1.43%) | 185 (7.58%) | 614 (25.14%) | |
The variables are presented as n (%) or the mean ± SD or median (quartile 1-quartile 3), TyG = Ln [TG (mg/dL) × FPG (mg/dL)/2], TyG-BMI = TyG × BMI
Abbreviations: TyG-BMI triglyceride glucose-body mass index, BMI body mass index, NAFLD non-alcoholic fatty liver disease, TyG triglyceride and glucose index, DBP diastolic blood pressure, SBP systolic blood pressure, DBIL direct bilirubin, TB total bilirubin, GLB globulin, GGT gamma-glutamyl transferase, TP total protein, ALB albumin, UA uric acid, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, Cr creatinine, BUN blood urea nitrogen, FPG fasting plasma glucose, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol