Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 28;11:85. doi: 10.1186/s13229-020-00385-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 3 — Mapping the Shank3 binding site on δ-catenin. a The domain structure of δ-catenin, and the truncated proteins used in this study. The Armadillo repeats are indicated in red and the binding sites for N-cadherin and PDZ ligands as well as the phosphorylation and palmitoylation sites are indicated by arrows. b GFP-tagged fragments of δ-catenin were coexpressed with RFP-tagged full-length Shank3. Cells were lysed and GFP-tagged proteins were immunoprecipitated using the GFP-trap matrix. Input and IP samples were analysed by Western blotting. The results show that the Arm repeats of δ-catenin bind to Shank3