Table 1.
Summary table
| Strain | 1 week | 2 week | 3 week | 4 week | ||||
|---|---|---|---|---|---|---|---|---|
| % of WT | p value | % of WT | p value | % of WT | p value | % of WT | p value | |
| MASP-2−/− | ||||||||
| Neuroscore | + 11.4 | 0.6079 | + 4.3 | 0.9605 | + 13.6 | 0.4541 | − 5.9 | 0.8809 |
| Beam Walk | + 5.5 | 0.9608 | + 27.9 | 0.0681 | + 32.1 | 0.0202 | + 36 | 0.0091 |
| MBL−/− | ||||||||
| Neuroscore | + 33.7 | 0.0997 | + 42.8 | 0.0023 | + 37.2 | 0.0011 | + 35.6 | 0.0003 |
| Beam Walk | + 12.9 | 0.2972 | + 24.03 | 0.0131 | + 25.1 | 0.0133 | + 21.4 | 0.0742 |
| FCN-A−/− | ||||||||
| Neuroscore | + 19.7 | 0.9253 | + 0.37 | > 0.9999 | − 7.9 | 0.7784 | + 5.3 | 0.9171 |
| Beam Walk | + 6.7 | 0.9253 | + 15 | 0.5412 | + 13 | 0.685 | + 9.9 | 0.829 |
| CL-11−/− | ||||||||
| Neuroscore | + 16 | 0.4086 | + 13.5 | 0.5552 | + 11.2 | 0.631 | + 11.9 | 0.5552 |
| Beam Walk | − 4.9 | 0.8735 | + 11.1 | 0.3198 | + 15.8 | 0.0711 | + 23.5 | 0.0024 |
| MBL-C−/− | ||||||||
| Neuroscore | + 10 | > 0.9999 | + 2.9 | > 0.9999 | + 11.1 | > 0.9999 | − 16.7 | 0.8796 |
| Beam Walk | − 3.5 | > 0.9999 | − 3.5 | > 0.9999 | 3.6 | > 0.9999 | + 3.9 | > 0.9999 |
| MASP-1/3−/− | ||||||||
| Neuroscore | + 9.1 | 0.9426 | + 11.9 | 0.784 | + 8.7 | 0.8759 | − 1.9 | 0.9976 |
| Beam Walk | + 1.07 | 0.9997 | + 0.56 | > 0.9999 | − 2.6 | 0.997 | 0 | > 0.9999 |
| MBL-A−/− | ||||||||
| Neuroscore | + 4.5 | 0.9986 | + 7.1 | 0.989 | − 2.9 | 0.9986 | − 19.5 | 0.589 |
| Beam Walk | − 10 | 0.9025 | − 4.2 | 0.9932 | − 9.8 | 0.9133 | − 11.01 | 0.8786 |
Summary of the outcome measures in the MASP-2−/−, MBL−/−, FCN-A−/−, CL-11−/−, MBL-C−/−, MASP-1/3−/− or MBL-A−/− TBI mice. For MBL−/−, data were obtained from the previous paper by Longhi et al. [32]