Table 3.

Multivariable Cox regression analysis of factors affecting risk of death in patients with ≥ 1 HAQ-DI measurement

Baseline parameter	HR	95% CI for HR	p value
HAQ-DI score	2.69	1.71, 4.23	< 0.001
Age at onset of RP	1.02	0.99, 1.04	0.177
mRSS	1.01	0.98, 1.04	0.527
Male gender	1.06	0.48, 2.35	0.888
Immunomodulator treatment	0.41	0.20, 0.84	0.014
Corticosteroids > 10 mg/day	5.41	2.10, 13.97	< 0.001
Advanced organ involvement (reference: no organ involvement)
One	3.57	1.77, 7.18	< 0.001
Multiple	4.81	1.73, 13.34	0.003

CI confidence interval, HAQ-DI Health Assessment Questionnaire-Disability Index, HR hazard ratio, mRSS Modified Rodnan Skin Score, RP Raynaud’s phenomenon