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. 2020 Oct 28;15(10):e0240452. doi: 10.1371/journal.pone.0240452

Table 3. Clinical and epidemiological characteristics of virus positive and negative groups.

Virus Positive (n = 25) Virus Negative (n = 45) p value
Median age in years (range +- SD) 3.9 (0.3–17,9; +- 4.9) 5,5 (0.3–17; +- 4.6) 0.3a
Median Days of symptoms (range+- SD) 6 (1–21; +-5.3) 6 (0–30; +-5.5) 0.7 a
Clinical Features
Change in Sinus Discharge 21 (84%) 26 (57.8%) 0.03
Worsening cough 25 (100%) 44 (97.8%) 1
Change in sputum pattern 22 (88%) 38 (84.4%) 1
Worsening dyspnea 14 (56%) 27 (60%) 0.8
Hemoptysis 1 (4%) 1 (2.2%) 1
Fatigue 9 (36%) 10 (22.2%) 0.21
Fever 16 (64%) 19 (42.2%) 0.08
Anorexia/weight loss 14 (56%) 26 (57.8%) 0.89
Sinus pain 1 (4%) 2 (4.4%) 1
Low oxygen saturation 7 (28%) 15 (33.3%) 0.65
Abnormal Chest Auscultation 20 (80%) 42 (93.3%) 0.1
Treatment
Antibiotics 19 (76%) 40 (88.9%) 0.18
Oseltamivir 1 (4%) 0 0.35
Oxygen therapy 6 (24%) 15 (33.3%) 0.41
Noninvasive Ventilation 3 (12%) 4 (8.9%) 0.69
Hospital Admission 10 (40%) 21 (46.7%) 0.11
Mean length of hospital stay in days (range +- SD) 14.6 (7–21; +- 3.8) 16,5 (8–34; +- 5.6) 0.45 a
Severity Scores
Mean CFCSc (range +- SD) 30.3 (19–39; +- 5.4) 29.4 (18–41; +- 5.9) 0.25b
Mean Shwachman-Kulczycki Score (range +- SD) 72.2 (45–95; +-11.9) 71.6 (35–90; +-12.4) 0.42 b

aStudent’s T test.

bMann Whitney’s U test.

cCystic Fibrosis Clinical Score.