Estimated probabilities up to 8% are shown for ovarian cancer, invasive ovarian cancer, and all cancers. CA125 levels that correspond to the closest integer probabilities of 3% are indicated. The probabilities, which equate to a CA125 level of 35 U/ml, are also marked. Confidence intervals (95%) are displayed. Graphs showing probabilities at an extended range of CA125 values (up to 500 U/ml) for ovarian cancer, invasive ovarian cancer, and all cancer are included in S1 Fig, S2 Fig, and S3 Fig, respectively. Data used to construct these graphs (up to a CA125 level of 1,000 U/ml) are available via the University of Cambridge Repository [27]. CA125, cancer antigen 125; CI, confidence interval.