Table 1. Baseline characteristics in waitlisted candidates without diabetes or cardiovascular disease (Groups 1 & 2) according to NISS status.
Stress Test | P | |||
---|---|---|---|---|
No | Yes | |||
Group 1 | Group 2 | |||
(n = 255) | (n = 368) | |||
Age: years | 36.7 (11.1) | 54.1 (11.8) | < 0.001 | |
BMI | 26.0 (4.5) | 26.8 (4.9) | 0.04 | |
Male (%) | 152 (59.6) | 191 (51.9) | 0.06 | |
Hypertension (%) | 209 (82.0) | 327 (88.9) | 0.02 | |
Non-Smoker (%) | 189 (74.1) | 210 (57.1) | < 0.001 | |
Ethnicity (%) | Caucasian | 197 (77.3) | 293 (79.6) | 0.48 |
Primary Disease (%) | Immune Kidney Disease | 71 (27.8) | 117 (31.8) | <0.01 |
Hypertensive CKD | 30 (11.8) | 58 (15.8) | ||
Polycystic Kidney Disease | 33 (12.9) | 67 (18.2) | ||
Other | 65 (47.5) | 76 (34.3) | ||
Previous Transplant (%) | 32 (12.6) | 56 (15.2) | 0.35 | |
Pre-emptive evaluation (%) | 211 (82.8) | 279 (75.8) | 0.38 | |
On Dialysis at evaluation (%) | 44 (17.2) | 89 (24.2) | ||
Pulmonary Disease (%) | 13 (5.1) | 34 (9.2) | 0.05 | |
Peptic ulcer disease (%) | 6 (2.4) | 21 (5.7) | 0.04 | |
Liver Disease (%) | 10 (3.9) | 12 (3.3) | 0.66 | |
Previous Cancer (%) | 8 (3.1) | 27 (7.3) | 0.03 | |
HIV (%) | 3 (1.2) | 2 (0.5) | 0.40 | |
Charlson Comorbidity Index | 2 (2,2) | 2 (2, 3) | < 0.001 | |
AHA risk factors (3 or more) | 80 (31.4) | 187 (50.8) | <0.001 | |
RAS inhibitors (%) | 168 (65.9) | 210 (57.1) | 0.03 | |
Statin (%) | 97 (38.0) | 203 (55.2) | < 0.001 | |
eGFR (ml/min/1.73m2) | 12.3 (5.0) | 11.6 (4.6) | 0.08 | |
Calcium (mmol/L) | 2.3 (0.2) | 2.3 (0.2) | 0.36 | |
Phosphate(mmol/L) | 1.4 (1.2, 1.7) | 1.4 (1.2, 1.7) | 0.38 | |
PTH (ng/L) | 199 (116, 343) | 200 (118, 355) | 0.80 | |
Albumin (g/L) | 40.4 (5.9) | 39.7 (5.6) | 0.12 | |
CRP (mg/L) | 3.2 (1.4, 6) | 5 (2.5, 8.2) | < 0.001 | |
Total Cholesterol (mmol/L) | 4.8 (4.0, 5.6) | 4.6 (2.4, 11.6) | 0.17 | |
HDL Cholesterol (mmol/L) | 1.2 (1.0, 1.5) | 1.3 (1.1, 1.7) | 0.03 | |
Total / HDL Cholesterol (mmol/L) | 3.8 (3.0, 4.7) | 3.4 (2.8, 4.4) | <0.01 |
Results shown as Mean (Standard Deviation), Median (IQR) for continuous variables and Number (Frequency) for categorical variables.
p-Value from Two Sample T-Test, Mann-Whitney U Test and Chi-Squared or Fisher’s Exact test as appropriate.