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. 2020 Oct 28;15(10):e0240912. doi: 10.1371/journal.pone.0240912

Table 1. Baseline characteristics in waitlisted candidates without diabetes or cardiovascular disease (Groups 1 & 2) according to NISS status.

Stress Test P
No Yes
Group 1 Group 2
(n = 255) (n = 368)
Age: years 36.7 (11.1) 54.1 (11.8) < 0.001
BMI 26.0 (4.5) 26.8 (4.9) 0.04
Male (%) 152 (59.6) 191 (51.9) 0.06
Hypertension (%) 209 (82.0) 327 (88.9) 0.02
Non-Smoker (%) 189 (74.1) 210 (57.1) < 0.001
Ethnicity (%) Caucasian 197 (77.3) 293 (79.6) 0.48
Primary Disease (%) Immune Kidney Disease 71 (27.8) 117 (31.8) <0.01
Hypertensive CKD 30 (11.8) 58 (15.8)
Polycystic Kidney Disease 33 (12.9) 67 (18.2)
Other 65 (47.5) 76 (34.3)
Previous Transplant (%) 32 (12.6) 56 (15.2) 0.35
Pre-emptive evaluation (%) 211 (82.8) 279 (75.8) 0.38
On Dialysis at evaluation (%) 44 (17.2) 89 (24.2)
Pulmonary Disease (%) 13 (5.1) 34 (9.2) 0.05
Peptic ulcer disease (%) 6 (2.4) 21 (5.7) 0.04
Liver Disease (%) 10 (3.9) 12 (3.3) 0.66
Previous Cancer (%) 8 (3.1) 27 (7.3) 0.03
HIV (%) 3 (1.2) 2 (0.5) 0.40
Charlson Comorbidity Index 2 (2,2) 2 (2, 3) < 0.001
AHA risk factors (3 or more) 80 (31.4) 187 (50.8) <0.001
RAS inhibitors (%) 168 (65.9) 210 (57.1) 0.03
Statin (%) 97 (38.0) 203 (55.2) < 0.001
eGFR (ml/min/1.73m2) 12.3 (5.0) 11.6 (4.6) 0.08
Calcium (mmol/L) 2.3 (0.2) 2.3 (0.2) 0.36
Phosphate(mmol/L) 1.4 (1.2, 1.7) 1.4 (1.2, 1.7) 0.38
PTH (ng/L) 199 (116, 343) 200 (118, 355) 0.80
Albumin (g/L) 40.4 (5.9) 39.7 (5.6) 0.12
CRP (mg/L) 3.2 (1.4, 6) 5 (2.5, 8.2) < 0.001
Total Cholesterol (mmol/L) 4.8 (4.0, 5.6) 4.6 (2.4, 11.6) 0.17
HDL Cholesterol (mmol/L) 1.2 (1.0, 1.5) 1.3 (1.1, 1.7) 0.03
Total / HDL Cholesterol (mmol/L) 3.8 (3.0, 4.7) 3.4 (2.8, 4.4) <0.01

Results shown as Mean (Standard Deviation), Median (IQR) for continuous variables and Number (Frequency) for categorical variables.

p-Value from Two Sample T-Test, Mann-Whitney U Test and Chi-Squared or Fisher’s Exact test as appropriate.