Fig 5. IFNβ induces a broader transcriptome than the IFNα subtypes.

(A) Interferome overlap between IFNα subtypes and IFNβ. IRGs from all 5 IFNα subtypes were combined, and compared to that of IRGs from IFNβ. The purple region corresponds to genes shared between the IFNα- and IFNβ-specific interferomes. A few ‘IFNβ-specific genes’ (yellow) were highlighted. (B) Predicted IFNβ pathways. Z-scores of various pathways predicted from IRGs of individual IFNα subtypes and IFNβ were compared. Rows labeled ‘Fig 4D’ corresponds to the ‘core pathways’ in Fig 4D.