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(A) Volcano Plot showing the FDR and fold-change criteria for altered core ISGs. Majority of the core ISGs were upregulated in PWH relative to HIV-uninfected controls. (B) Gene categories of altered core ISGs. (C) TMM values of representative antiviral, innate sensing, negative feedback and immunomodulatory genes. Floating bars correspond to min and max values, with the central line corresponding to the mean.
