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. 2020 Oct 16;16(10):e1008986. doi: 10.1371/journal.ppat.1008986

Fig 9. Core and IFNβ-specific ISGs that correlated with immunopathogenic markers of chronic HIV-1 infection.

Fig 9

(A-D; panels on the left half) Correlations between select Core ISGs (A) IRF9, (B) CD38, (C) NLRC5 and (D) LAG3 and clinically relevant parameters. (E-I; panels on the right half) Correlations between select IFNβ-specific ISGs (E) EIF4H, (F) SMAD4, (G) VIMP, (H) NUP54 and (I) MUS81 and clinically relevant parameters. Expression levels were based on TMM-transformed counts. Linear regression was performed in R statistical package, adjusting for age and gender. A full list of the proportion of core and IFNβ-specific genes that correlated with clinical parameters is presented in S11 Table.