Table 1.
Dose objectives and results for single fraction and three fraction plans generated automatically for ten cases.
| Structure | Dose objective (1fx) | Result (1fx) | Dose objective (3fx) | Result (3fx) |
|---|---|---|---|---|
| GTV (n = 10) | V100% ≥ 95% | 87.3% (76.2%, 97.2%) | V100% ≥ 95% | 95.6% (89.1%, 99.3%) |
| Dmax < 130% | 122.3% (114.1%, 130.3%) | Dmax < 130% | 124.8% (111.0%, 130.2%) | |
| CTV (n = 10) | V100% ≥ 90‐80% | 95.7% (79.7%, 100%) | V100% ≥ 90‐80% | 99.6% (97.9%, 100.0%) |
| PTV (n = 10) | V100% ≥ 90‐80% | 88.0% (74.9%, 100%) | V100% ≥ 90‐80% | 97.2% (92.9%, 95.6%) |
| Spinal Cord (n = 9) | D0.035cc < 1000cGy | 934.0 (808.3, 979.1) cGy | D0.035cc < 2190cGy | 1313.8 (1009.2, 1765.0) cGy |
| V800cGy < 1cc | 0.470 (0.054, 0.919) cc | V1230cGy < 1.2cc | 0.105 (0.0, 0.537) cc | |
| Spinal Cord + 2mm (n = 9) | D0.035cc < 1200cGy | 1079.9 (938.0, 1177.4) cGy | D0.035cc < 2390cGy | 1846.2 (1603.3, 2080.5) cGy |
| V1000cGy < 1cc | 0.328 (0.0, 0.992) cc | V1430cGy < 1.2cc | 0.451 (0.197, 0.936) cc | |
| Esophagus (n = 8) | D0.035cc < 1700cGy | 1294.4 (549.3, 1619.3) cGy | D0.035cc < 2520cGy | 1737.8 (646.2, 2277.0) cGy |
| V1200cGy < 1cc | 0.249 (0.0, 0.712) cc | V1770cGy < 5cc | 0.006 (0.0, 0.742) cc | |
| Heart (n = 5) | D0.035cc < 2200cGy | 689.1 (231.5, 1318.8) cGy | D0.035cc < 3000cGy | 923.6 (276.8, 1831.6) cGy |
| V1600cGy < 15cc | 0.0 (0.0, 0.0) cc | V2400cGy < 15cc | 0.0 (0.0, 0.0) cc | |
| Skin (n = 8) | D0.035cc < 1600cGy | 758.8 (487.9, 1066.0) cGy | D0.035cc < 3300cGy | 985.3 (684.4, 1391.8) cGy |
| V1400cGy < 10cc | 0.0 (0.0, 0.0) cc | V3000cGy < 10cc | 0.0 (0.0, 0.0) cc | |
| Lungs (n = 6) | MVS700cGy > 1000cc | 2207.0 (1886.4, 3228.2) cc | MVS1160cGy > 1500cc | 2262.7 (1895.0, 3238.0) cc |
| Liver (n = 4) | MVS910cGy > 700cc | 1882.9 (887.6, 3428.2) cc | MVS1920cGy > 700cc | 1882.9 (911.1, 3428.2) cc |
| Trachea (n = 3) | D0.035cc < 2020cGy | 1086.5 (860.1, 1467.1) cGy | D0.035cc < 3000cGy | 1436.8 (1166.8, 2057.9) cGy |
| V880cGy < 4cc | 0.892 (0.012, 3.202) cc | V1500cGy < 4cc | 0.005 (0.0, 1.932) cc | |
| Brachial Plexus, Right (n = 2) | D0.035cc < 1600cGy | 1547.1 (1546.2, 1548.0) cGy | D0.035cc < 2400cGy | 2211.6 (2198.5, 2224.7) cGy |
| V1400cGy < 3cc | 0.440 (0.294, 0.585) cc | V2040cGy < 3cc | 0.173 (0.154, 0.192) cc | |
| Brachial Plexus, Left (n = 2) | D0.035cc < 1600cGy | 1498.6 (1449.2, 1548.0) cGy | D0.035cc < 2400cGy | 2125.3 (2057.1, 2193.4) cGy |
| V1400cGy < 3cc | 0.205 (0.059, 0.350) cc | V2040cGy < 3cc | 0.138 (0.041, 0.235) cc | |
| Cauda Equina (n = 1) | D0.035cc < 1600cGy | 1177.8 cGy | D0.035cc < 2400cGy | 2050.9 cGy |
| V1200cGy < 1cc | 0.009 cc | V2190cGy < 5cc | 0.0 cc | |
| Cauda Equina + 2mm (n = 1) | D0.035cc < 1800cGy | 1424.6 cGy | D0.035cc < 2600cGy | 2409.1 cGy |
| V1400cGy < 1cc | 0.057 cc | V2390cGy < 5cc | 0.054 cc |
Median values with range (minimum, maximum) in parentheses.