Table 2. Adjusted Multivariate Risk of Frequent PACs for Subsequent 5-Year Clinical Events.

	Event rate at 5 year (unadjusted)		Adjusted HR of frequent PACs (95% CI)	p value
	Without frequent PACs (n=180)	With frequent PACs (n=210)
Composite events	7.2% (13)	15.2% (32)	2.30 (1.16–4.56)	0.017
New-onset atrial fibrillation	1.1% (2)	4.8% (10)	5.34 (1.10–25.85)	0.037
Recurrent stroke	6.1% (11)	11.4% (24)	1.99 (0.94–4.20)	0.072

HR, hazard ratio; PAC, premature atrial contractions; CI, confidence interval.

Rates are Kaplan-Meier estimates at 5 year (number of events). P-value corresponds to the adjusted HR (95% CI). All clinical endpoints were adjusted by age, sex.

EF, diastolic dysfunction (E/e' >14), LAVi, hypertension, diabetes, coronary artery disease, chronic kidney disease, cigarette smoking status, and frequent PACs.