Figure 7.

Summary of the ion dependency and E129A mutation of hWR-W163F. (A) Comparison of the extrapolated I_peak zero-current potential among hWR-W163F in a standard milieu (Control), in a low Na⁺/Cl^– milieu (NMG) and that of hWR-E129A-W163F in a low Na⁺/Cl^– milieu (E129A). Box and whisker graphs for the first responses (blue symbols) and the second responses (red symbols). (B) Similar to A, but comparison of the I_end' reversal potential. (C) Similar to A, but comparison of R_e/p, the amplitude ratio of I_end'(–80)/I_peak(80). (D) Similar to A, but comparison of R_s/p, the amplitude ratio of I_shift(80)/I_peak(80). * and **, p<0.05 and p<0.005, Mann-Whitney U-test. ^† and ^††, p<0.05 and p<0.005, Wilcoxon signed rank test.