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| Reclassification | Patients with BRCA1 VUS (n=82) | Patients with BRCA2 VUS (n=90) | Patients with BRCA1 VUS+BRCA2 VUS (n=23) | Total (n=195) |
|---|---|---|---|---|
| Benign | 26 (31.7) | 20 (22.2) | 3 (13.0) | 49 (25.1) |
| Likely benign | 3 (3.7) | 24 (26.7) | 5 (21.7) | 32 (16.4) |
| VUS | 39 (47.6) | 42 (46.6) | 13 (56.5) | 94 (48.2) |
| Likely pathogenic | 5 (6.1) | 4 (4.4) | 1 (4.3) | 10 (5.1) |
| Pathogenic | 9 (11.0) | 0 (0.0) | 1 (4.3) | 10 (5.1) |
VUS, variants of unknown.
