Table 1.

Characteristics of six treatment refractory PPPP patients treated with apremilast.

Case	Age (years)	Sex	PGA at baseline	PGA at follow-up endpoint	Follow-up (months)	Disease duration (years)	Smoking history	Concomitant disease
1	76	Female	3	1	18	33	positive	PsA, fibromyalgia
2	56	Female	4	1	18	7	negative	PsA, arterial hypertension, type II diabetes, depression, obesity
3	48	Male	3	1	18	6	positive	Depression, arterial hypertension
4	36	Female	3	0	6	12	positive	PsA
5	73	Female	3	1	18	18	positive	PsA, arterial hypertension, Hypothyreosis, Asthma
6	48	Male	4	0 (soles) 1 (palms)	6	6	positive	PsA, depression