Table 3.

Multivariate analysis of overall survival in colorectal cancer patients with mpN stage.

Variables	Training cohort		Validation cohort
	HR (95% CI)	P-value	HR (95%CI)	P-value
Location	0.954 (0.863–1.054)	0.351	0.943 (0.810–1.098)	0.449
Sex	1.129 (1.048–1.217)	0.001	1.210 (1.077–1.360)	0.001
Race	0.999 (0.947–1.053)	0.961	0.977 (0.900–1.060)	0.569
Age	1.690 (1.566–1.823)	<0.001	1.618 (1.439–1.819)	<0.001
Size	1.112 (1.039–1.191)	0.002	1.159 (1.042–1.288)	0.006
Grade	1.224 (1.165–1.286)	<0.001	1.244 (1.155–1.341)	<0.001
T stage	1.524 (1.455–1.597)	<0.001	1.409 (1.314–1.511)	<0.001
TD status	1.025 (1.016–1.034)	<0.001	1.019 (1.006–1.033)	0.006
mpN stage	1.339 (1.292–1.388)	<0.001	1.393 (1.318–1.473)	<0.001

CI, confidence interval; HR, hazard ratios; mpN, modified pN; mTNM, modified TNM; TD, tumor deposit.