Table 2.

Risk of Bias in the included cohort studies according to Methodological Index for Non-Randomized Studies (MINORS) criteria [16]

	Wilson et al. [36]	Wilson et al. [34]	Wintermeyer et al. [35]	Ihle et al. [33]	Müller et al. [26]	Goisser et al. [27]	Chakravarty et al. [28]	Banks et al. [29]	Dhandapani et al. [25]	Goiburu et al. [10]	Compan et al. [30]	McClave et al. [31]	Kaufman et al. [32]
1. Clearly stated aim	2	2	2	2	2	2	2	2	2	2	2	1	2
2. Inclusion of consecutive patients	2	2	2	2	2	2	2	2	2	2	2	0	0
3. Prospective collection of data	2	2	2	2	2	2	0	2	2	2	2	2	0
4. Endpoints appropriate to aim of study	2	2	2	2	2	2	2	2	2	2	2	0	2
5. Unbiased assessment of study endpoints	2	2	2	0	2	0	0	2	2	0	1	0	0
6. Follow-up period appropriate to aim of study	2	2	2	2	2	2	2	2	2	2	2	2	2
7. < 5% lost to follow-up	2	1	2	2	0	2	2	1	1	1	0	2	1
8. Prospective calculation of study size	0	0	0	0	2	2	2	1	1	1	1	0	0
Total	14	13	14	12	14	14	12	14	14	12	12	7	7

Criteria were scored 2 (reported and adequate), 1 (reported but inadequate) or 0 (not reported), with a maximum total score of 16