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. 2020 Oct 15;11:01320. doi: 10.3389/fphar.2020.01320

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Copyright © 2020 Chen, Zhang, Hu, Zhang, Zhang, Kan, Li and Du

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein-protein interaction (PPI) network of anxiolytic effects-related targets of SZJ. Cytoscape (Version 3.6.1) was applied to construct the interactions downloaded from the STRING (interaction score set as high confidence >0.7). All the targets are represented by nodes, whereas the interactions between the targets are represented by edges. MCODE plug-in was applied to conduct cluster analysis. Different clusters are noted with different colors. The node size is proportional to its located cluster MCODE score.