Overview of a Bioreactor Connected to Hollow Fiber Filter Cell Separation for Perfusion Process by TFF or ATF
Schematic diagram of (A) tangential flow filtration, TFF, where pump 1 was an Alitea XV pump with a flow rate of up to 0.19 L/min, or two Alitea XV pumps mounted in parallel for 0.38 L/min, or the diaphragm pump of an ATF2 mounted with two one-way valves for flow rates >0.38 L/min; (B) alternating tangential flow filtration, ATF.