Figure 5.

Effect of Different Flow Rates in ATF and TFF Systems on the Cell Specific Glucose Consumption Rate, q_gluc, the Cell Specific Lactate Production Rate, q_lac, and the Ratio q_lac/q_gluc

(A) q_gluc as function of the flow rate.

(B) q_gluc as function of the shear rate calculated by Equations 1 and S15.

(C) q_lac as function of the flow rate.

(D) q_lac as function of the shear rate.

(E) q_lac/q_gluc as function of the flow rate.

(F) q_lac/q_gluc as function of the shear rate – all rates were averages of the values at days 2 and 3; the error bars give the variation in repeated experiments and control is absence of flow 'No shear'