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Timeline of experiments (A) and site of irritant instillation (in this case formalin) shown on opened nasal cavity (septum was removed) of rat injected with Evans blue and perfused with saline (B). Formalin instillation site is situated near the entrance to the paranasal sinus and is marked with the red arrow. Near it marked Evans blue extravasation can be observed when comparing to contralateral side.
