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. 2020 Oct 15;7:579874. doi: 10.3389/fmolb.2020.579874

Figure 5.

Figure 5

Kaplan–Meier analysis of progression-free survival according to CXCL10 and CXCR3 expression levels in primary PC. Patients with CXCL10 levels between 0–25% were grouped into quartile 1, 25–50% into quartile 2, 50–75% into quartile 3, and 75–100% into quartile 4. CXCR3 levels were also classified into quartiles. Postoperative disease-free survival outcomes for each group are provided in this figure. When CXCL10 was grouped into quartiles, patients in the first quartile had better prognoses than those in other quartiles (p = 0.0747). When CXCR3 was grouped into quartiles, patients in the fourth quartile had significantly poorer prognoses than those in the other quartiles (p = 0.0095). These results supported designating the first CXCL10 quartile as “low” and the other as “high.” Likewise, the first, second, and third quartiles of CXCR3 were designated as “low” and the fourth quartile as “high.” Patients with both CXCL10 high and CXCR3 high (CXCL10/CXCR3 co-expression) had significantly poorer prognoses than those scored as “low” for both CXCL10 and CXCR3 (p = 0.0067).