Table 1.
List of the CXC Chemokine ligands and chemokine receptors.
| E-L-R amino acid motif | Chemokine | Receptor |
|---|---|---|
| ELR− | CXCL4 (PF4) | CXCR3B |
| CXCL9 | CXCR3A, CXCR3B | |
| CXCL10 | CXCR3A, CXCR3B | |
| CXCL11 | CXCR3A, CXCR3B, CXCR7 (ACKR3) | |
| CXCL12 | CXCR4, CXCR7 (ACKR3) | |
| CXCL13 | CXCR 5>> CXCR3 | |
| CXCL16 | CXCR6 | |
| ELR+ | CXCL1 | CXCR2 |
| CXCL2 | CXCR2 | |
| CXCL3 | CXCR2 | |
| CXCL5 | CXCR2 >> CXCR1 | |
| CXCL6 | CXCR2 > CXCR1 | |
| CXCL7 (PPBP) | CXCR1, CXCR2 | |
| CXCL8 (IL-8) | CXCR1, CXCR2 | |
| CXCL14 | Unknown | |
| CXCL15 | Unknown |
CXC chemokines and corresponding receptors are categorized by the presence or absence of the glutamate-leucine-arginine (ELR) motif within the three amino acid residues proximal to the CXC sequence.