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. 2020 Oct 15;10:554331. doi: 10.3389/fonc.2020.554331

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Copyright © 2020 Zhang, Fan, Wang, Yang, Wu, Huang, Lan, Liao, Huang, Yuan, Pan, Wu, Chen and Guan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The correlation between CHST4 and immune cell infiltration in HBV-HCC. (A) The degree of immune infiltration in HBV-HCC was evaluated by TIMER platform (TIMER, QUANTISEQ, MCPCOUNTER, and EPIC databases). Bar represents the mean ± SD; *P < 0.05, **P < 0.01 (Student’s t-test). (B) The immune cell infiltration score in HBV-HCC using R-ssGSEA (Tcm, T central memory cells; Tem, T effector memory cells; Th1 cells, T helper 1 cells; Th2 cells, T helper 2 cells; TFH, T follicular helper cells; Th17 cells, T helper 17 cells; Treg, regulatory T cells; Tgd, T gamma delta cells; NK cells, natural killer cells; DC, dendritic cell; iDC, immature DC; aDC, activated DC; pDC, plasmacytoid DC). Bars represent the mean ± SD; *P < 0.05, **P < 0.01, ***P < 0.001 (Student’s t-test).