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. 2020 Oct 15;11:595454. doi: 10.3389/fneur.2020.595454

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Copyright © 2020 Zaher, Urban, Antony, Plummer, Bagić, Richardson and Kokkinos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Raw iEEG (left, A₁-E₁) from the MT contacts and respective time-frequency analysis (right, A₂-E₂) of seizure onsets in patients with poor outcome. (A₁,A₂) Patient 1 with Engel Class IIIA outcome. (B₁,B₂) Patient 2 with Engel Class IVB outcome. (C₁,C₂) Patient 3 with Engel Class IVB outcome. (D₁,D₂) Patient 7 with Engel Class IVB outcome. (E₁,E₂) Patient 8 with Engel Class IIIA outcome. Notice the rise in frequency content with a peak indicated by asterisks, following ictal onset (at time = 0).