Table 1.

Clinical and demographic characteristics of all LARC patients.

Characteristic		N	%
Age	Median (range yrs.)	66 (31–79)
Sex	Male	52	63%
	Female	30	37%
Tumor distance from anal verge	≤ 7 cm	26	32%
	>7 cm	39	48%
	Not available	17	20%
TRG	1–2	37	45%
	3–5	45	55%
Specimens	Plasma	45
	Tissues	69
Paired samples	Plasma–tumor samples	32
	Healthy mucosa–tumor samples	13

Tumor regression grade (TRG) is calculated according to Mandard et al. (32). TRG 1–2, responders; TRG 3–5, nonresponders.