Table 1.
Patient characteristics.
| Variables | Total (n = 301) | ENPH (n = 69) | ENAH (n = 164) | NN (n = 68) | P value |
|---|---|---|---|---|---|
| Age (years) | 32.4 ± 11.7 | 31.8 ± 11.5 | 32.5 ± 11.7 | 32.7 ± 12.1 | 0.893 |
| Female | 121 (40.2) | 32 (46.4) | 70 (42.7) | 19 (27.9) | 0.056 |
| BMI (kg/m2) | 21.1 ± 3.7 | 21.5 ± 3.3 | 20.8 ± 3.5 | 21.6 ± 4.4 | 0.237 |
| Haemodynamics | |||||
| Systolic BP (mmHg) | 114.5 ± 10.6 | 114.3 ± 10.5 | 114.7 ± 10.9 | 114.3 ± 10.0 | 0.958 |
| Diastolic BP (mmHg) | 70.5 ± 12.5 | 70.4 ± 12.3 | 70.6 ± 12.7 | 70.3 ± 12.6 | 0.985 |
| Heart rate (beats/min) | 83.5 ± 11.9 | 83.64 ± 13.3 | 83.8 ± 11.7 | 82.5 ± 11.0 | 0.740 |
| LVEF (%) | 61.1 ± 9.3 | 60.3 ± 8.7 | 61.10 ± 9.4 | 61.92 ± 9.6 | 0.633 |
| LVEDD (mm) | 43.0 ± 4.60 | 42.9 ± 3.9 | 42.87 ± 4.8 | 43.28 ± 4.9 | 0.827 |
| Laboratory values | |||||
| Sodium (mEq/L) | 137.5 ± 3.0 | 137.9 ± 3.3 | 137.6 ± 3.0 | 136.9 ± 2.7 | 0.149 |
| Uric acid (mg/dL) | 3.4 ± 1.6 | 3.3 ± 1.5 | 3.2 ± 1.5 | 3.86 ± 1.8 | 0.011 |
| eGFR (mL/min/1.73m2) | 161.2 ± 59.7 | 149.3 ± 48.9 | 163.7 ± 59.7 | 167.0 ± 68.2 | 0.159 |
| NT-proBNP (pg/mL) (baseline) | 55.0 (30.0, 112.0) | 70.0 (31.0, 119.0) | 59.0 (37.25, 119.0) | 33.50 (23.8, 55.0) | <0.001 |
| NT-proBNP (pg/mL) (post-HSCT) | 415.0 (141.0, 1283.0) | 1055.0 (374.0, 5155.0) | 538.5 (254.5, 1366.0) | 55.0 (38.0, 81.3) | <0.001 |
| Hemoglobin (g/dL) | 89.2 ± 20.7 | 83.4 ± 18.6 | 87.1 ± 19.9 | 100.0 ± 20.9 | <0.001 |
Values are mean ± SD, n (%), or median (interquartile range). ENPH: elevated NT-proBNP and presence of clinical signs or symptoms of heart failure; ENAH: elevated NT-proBNP but absence of symptoms or signs of heart failure; NN: normal NT-proBNP; BMI: body mass index; BP: blood pressure; LVEF: left ventricle ejection fraction; LVEDD: left ventricular end-diastolic diameter; eGFR: estimated glomerular filtration rate; NT-proBNP: N-terminal probrain natriuretic peptide.