Table 3.
Complication rates reported for OVDs.
| Author (year) | OVDs | N (eyes) | Adverse events (rates in %) |
|---|---|---|---|
| Auffarth (2017) | Twinvisc | 109 | Ocular hypertension (12.6%), corneal edema (0.9%), cystoid macular edema (0.9%); IOP ≥ 30 mmHg in 6 hours postop (6.5%), 24 hours (0.9%), 7 days (0.9%), 30 days (0%), 90 days (0%) |
|
| |||
| DuoVisc | 111 | Ocular hypertension (17.6%), corneal edema (0.9%), inflammation (0.9%), capsule break (0.9%), bubbles in Viscoat OVD (0.9%); IOP ≥ 30 mmHg in 6 hours postop (7.2%), 24 hours (0%), 7 days (0%), 30 days (0%), 90 days (0%) | |
|
| |||
| Espindola (2012) | DisCoVisc | 39 | No intraoperative and postoperative complications |
| 2% HPMC | 39 | ||
|
| |||
| Hutz (1996) | Methocel | 50 | Pressure peaks up to 44 mm·Hg requiring acetazolamide (Diamox) treatment occurred twice in the Healon GV group and once in the Healon group postoperatively. Peaks up to 38 mm·Hg occurred three times in the Viscoat group, and peaks up to 35 mm Hg occurred six times in the Methocel group |
| Viscoat | 50 | ||
| Healon | 50 | ||
| Healon GV | 50 | ||
|
| |||
| Oshika (2004) | Healon5 | 78 | IOP elevation (5.1%), corneal edema (2.5%), nausea and vomiting (1.3%) |
| Healon | 79 | IOP elevation (1.3%), corneal edema (1.3%) | |
|
| |||
| Oshika (2010) | DisCoVisc | 154 | IOP ≥ 30 mmHg in 5 h postop (7.2%) |
| Healon5 | 163 | IOP ≥ 30 mmHg in 5 h postop (7.4%), mild corneal edema (0.6%), macular edema (0.6%) | |
|
| |||
| Ray-Chaudhary (2006) | Ophthalin | 51 | No significant difference in the number of complications between the two groups |
| HPMC-Ophtal | 52 | ||
|
| |||
| Rainer (2007) | NaHa 1% | 40 | IOP ≥ 30 mmHg in 30 mins postop (3%), 1 hour postop (5%), 2 hours postop (3%), 3 hours postop (5%), 4 hours postop (8%), 6 hours postop (13%), 8 hours postop (8%), 20–24 hours postop (0%) |
| 2% HPMC | 40 | IOP ≥ 30 mmHg in 30 mins postop (8%), 1 hour postop (13%), 2 hours postop (23%), 3 hours postop (13%), 4 hours postop (8%), 6 hours postop (10%), 8 hours postop (10%), 20–24 hours postop (0%) | |
|
| |||
| Thirumalai (2007) | Healon GV | 415 | In 2 hours follow-up: IOP ≥ 30 mmHg (7.2%), IOP ≥35 mmHg (4%). In 24-hour follow-up: IOP ≥ 30 mmHg (8.8%), IOP ≥ 35 mmHg (4%). In 2-day follow-up: IOP ≥30 mmHg (7%), IOP ≥ 35 mmHg (3.5%) |