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. 2019 Dec 9;21(10):2237–2243. doi: 10.1093/pm/pnz304

Table 1.

Prescription opioid misuse motive prevalence by age group (N = 5,826)

Motives* Adolescents (12–17 y; A) Young Adults (18–25 y; B) 26–34 y (C) 35–49 y (D) ≥50 y (E) Pairwise Comparisons
Sample size (N = 977) (N = 2,156) (N = 1,229) (N = 1,049) (N = 415)
% (95% CI) % (95% CI) % (95% CI) % (95% CI)
To relieve pain 56.1 (51.9–60.3) 59.6 (56.6–62.5) 69.7 (66.6–72.7) 76.4 (73.5–79.0) 84.7 (79.1–89.0) A, B < C < D < E
To relax 27.8 (24.1–31.7) 32.5 (29.7–35.4) 31.6 (28.5–34.9) 23.2 (20.4–26.3) 17.4 (12.7–23.3) D, E < A, B, C
To experiment 15.6 (12.8–18.8) 12.5 (10.7–14.4) 5.4 (3.7–7.6) 1.7 (0.9–3.0) 1.4 (0.7–3.1) D, E < C < B < A
To get high 25.8 (22.5–29.4) 31.9 (29.7–34.2) 25.8 (22.5–29.4) 16.1 (13.2–19.5) 6.9 (4.7–10.2) E < D < C < B;E, D < A
To sleep 14.4 (12.0–17.2) 17.4 (15.1–20.0) 14.9 (12.1–18.1) 12.6 (10.3–15.2) 16.4 (12.5–21.2) D < B
To help with emotions 14.1 (11.3–17.4) 14.1 (12.3–16.0) 10.8 (9.1–12.7) 8.7 (6.8–11.0) 6.3 (4.1–9.7) D, E < A, B;E < C;C < B
To alter other drug effects 2.0 (1.2–3.3) 3.7 (3.1–4.5) 3.0 (1.9–4.5) 1.5 (0.8–2.8) 1.2 (0.5–2.9) D, E < B
Because I am “hooked” 0.9 (0.4–1.9) 3.2 (2.3–4.4) 5.6 (4.3–7.3) 3.4 (2.3–5.0) 1.5 (0.7–3.4) A < B, C, D;B, D, E < C
Other reason 5.2 (3.8–7.1) 2.6 (1.8–3.7) 2.2 (1.5–3.2) 3.0 (2.0–4.4) 1.3 (0.5–3.4) B, C, D, E < A
Motive category
 Pain relief only 38.4 (34.4–42.6) 35.1 (32.2–38.2) 43.6 (39.9–47.5) 55.0 (51.3–58.7) 65.4 (58.6–71.6) Base outcome
 Non–pain relief only 43.9 (39.7–48.2) 40.4 (37.5–43.4) 30.3 (27.3–33.4) 23.7 (21.0–26.6) 15.3 (11.0–20.9) E < D < C < A, B
 Mixed motives 17.7 (14.8–21.1) 24.5 (21.9–27.3) 26.1 (22.8–29.6) 21.4 (18.3–24.8) 19.3 (15.2–24.2) D, E < B, C;E < A;A < B

Source: 2015–16 NSDUH surveys.

CI = confidence interval; NSDUH = National Survey on Drug Use and Health; POM = prescription opioid misuse.

*

Individual opioid motives are not mutually exclusive (i.e., “select as many as apply”) and are from the last POM episode in those with past-year POM.

Motive category variables are mutually exclusive and are based on the individual opioid motives selected by respondents.

Pairwise comparisons are based on logistic or multinomial logistic models that control for sex, race/ethnicity, household income, and population density of residence; significant listed differences are Bonferroni-corrected for 10 comparisons (P 0.005).