TABLE 3.
The enriched functions of the 15 genes from tumor tissues, the 11 genes from adjacent tissues, and the combined 26 genes using GATHER.
| Function | # Genes | Genes | p value | Bayes factor | ||
| The 15 genes from tumor | Gene Ontology | GO:0016043: cell organization and biogenesis | 3 | HIST1H4G NPHP1 SOCS4 | 0.0004 | 4 |
| GO:0006996: organelle organization and biogenesis | 2 | HIST1H4G NPHP1 | 0.006 | 2 | ||
| V$HEN1_02: HEN1 | 2 | NPHP1 SOCS4 | 0.0003 | 4 | ||
| TRANSFAC | V$NFKB_Q6: NF-kappaB | 3 | DOCK9 NPHP1 SOCS4 | 0.002 | 3 | |
| V$HNF1_Q6 | 2 | NPHP1 SOCS4 | 0.004 | 2 | ||
| The 11 genes from adjacent | KEGG Pathway | hsa04060: Cytokine-cytokine receptor interaction | 1 | TNFRSF14 | 0.002 | 2 |
| TRANSFAC | V$USF_01: upstream stimulating factor | 4 | ATF3 CREB5 TNFRSF14 XPO1 | <0.0001 | 7 | |
| V$MYC_Q2 | 4 | ATF3 CREB5 TNFRSF14 XPO1 | 0.0002 | 5 | ||
| V$NMYC_01: N-Myc | 4 | ATF3 CREB5 TNFRSF14 XPO1 | 0.0004 | 4 | ||
| V$MYCMAX_02: c-Myc:Max heterodimer | 4 | ATF3 CREB5 TNFRSF14 XPO1 | 0.001 | 3 | ||
| V$AML_Q6 | 3 | ATF3 CREB5 TNFRSF14 | 0.002 | 2 | ||
| V$SRF_Q6: serum response factor | 2 | ATF3 CREB5 | 0.003 | 2 | ||
| Combined 26 genes | TRANSFAC | V$NFKB_Q6: NF-kappaB | 5 | CREB5 DOCK9 NPHP1 SOCS4 XPO1 | 0.0008 | 3 |