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. 2020 Oct 15;11:554502. doi: 10.3389/fgene.2020.554502

TABLE 3.

The enriched functions of the 15 genes from tumor tissues, the 11 genes from adjacent tissues, and the combined 26 genes using GATHER.

Function # Genes Genes p value Bayes factor
The 15 genes from tumor Gene Ontology GO:0016043: cell organization and biogenesis 3 HIST1H4G NPHP1 SOCS4 0.0004 4
GO:0006996: organelle organization and biogenesis 2 HIST1H4G NPHP1 0.006 2
V$HEN1_02: HEN1 2 NPHP1 SOCS4 0.0003 4
TRANSFAC V$NFKB_Q6: NF-kappaB 3 DOCK9 NPHP1 SOCS4 0.002 3
V$HNF1_Q6 2 NPHP1 SOCS4 0.004 2
The 11 genes from adjacent KEGG Pathway hsa04060: Cytokine-cytokine receptor interaction 1 TNFRSF14 0.002 2
TRANSFAC V$USF_01: upstream stimulating factor 4 ATF3 CREB5 TNFRSF14 XPO1 <0.0001 7
V$MYC_Q2 4 ATF3 CREB5 TNFRSF14 XPO1 0.0002 5
V$NMYC_01: N-Myc 4 ATF3 CREB5 TNFRSF14 XPO1 0.0004 4
V$MYCMAX_02: c-Myc:Max heterodimer 4 ATF3 CREB5 TNFRSF14 XPO1 0.001 3
V$AML_Q6 3 ATF3 CREB5 TNFRSF14 0.002 2
V$SRF_Q6: serum response factor 2 ATF3 CREB5 0.003 2
Combined 26 genes TRANSFAC V$NFKB_Q6: NF-kappaB 5 CREB5 DOCK9 NPHP1 SOCS4 XPO1 0.0008 3