Fig. 1. Cu(ii) supplementation increases the potency of a subset of HCT compounds. MIAPACA2 cells were treated with HCT compound with 20 μM CuCl2 supplementation or with HCT compound alone (compound-only IC90 value shown in parentheses) for 72 h. Cell viability was then measured with CellTiter-Glo and IC90 values determined. Lead compound HCT-13 is highlighted.
