Table 5. Antischistosomal properties of some promising compounds (contd.).

Compound a	Schistosoma species	Life cycle stage	Worm death b (%)	SmTGR (IC50, μM)
171 181	S. mansoni	Larva	100	3.15
		Adult	100
172 182	S. mansoni	Larva	99	0.33
		Juvenile	39
		Adult	62
	S. japonicum	Adult	65
	S. haematobium	Adult	67
173 182	S. mansoni	Larva	100	0.21
		Juvenile	100
		Adult	78
	S. japonicum	Adult	50
	S. haematobium	Adult	94
174 181,182	S. mansoni	Larva	100	2.84
		Juvenile	100
		Adult	100
	S. japonicum	Adult	70
	S. haematobium	Adult	100
175 181,182	S. mansoni	Larva	100	2.01
		Juvenile	100
		Adult	76
	S. japonicum	Adult	69
	S. haematobium	Adult	85
176 182	S. mansoni	Larva	100	0.06
		Juvenile	57
		Adult	67
	S. japonicum	Adult	30
	S. haematobium	Adult	48
177 182	S. mansoni	Larva	96	0.14
		Juvenile	100
		Adult	28
	S. japonicum	Adult	100
178 182	S. mansoni	Larva	20	0.13
		Juvenile	24
		Adult	53
	S. japonicum	Adult	56

^aReference.

^bPercent worm death after 24–144 h of 10–12.5 μM of test compound.