Table 2.
Overall Survival analyses of the established CLL biomarkers (age, 17p deletion, and IGHV status) and the DRAK2 expression.
| Covariate | HR | STD Err | p-Value | Conf. Interval | HR | STD Err | p-Value | Conf. Interval | ||
|---|---|---|---|---|---|---|---|---|---|---|
| Univariate Analysis | Multivariate Analysis | |||||||||
| Age > 70 years | 1.05 | 0.02 | 0.014 | 1.01 | 1.091 | 1.094 | 0.026 | 0.001 | 1.04 | 1.151 |
| 17p status | 3.681 | 0.542 | 0.016 | 1.273 | 10.65 | 3.188 | 0.619 | 0.06 | 0.947 | 10.729 |
| IGHV status | 3.093 | 0.418 | 0.007 | 1.363 | 7.02 | 5.514 | 0.473 | 0.0003 | 2.183 | 13.925 |
| DRAK2 expression | 0.343 | 0.379 | 0.005 | 0.163 | 0.722 | 0.428 | 0.427 | 0.04 | 0.185 | 0.987 |