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mRNA expression of SOD1, SOD2 and catalase in neuronal differentiated cells. (a) SOD1 mRNA and (b) SOD2 mRNA expressions in NPC1-deficient cell lines were not different in comparison to the control (n = 5 or 6). (c) All NPC1-deficient cell lines showed a significantly lower expression of catalase mRNA (n = 6). * = p < 0.05 and ** = p < 0.01. Statistical tests used: (a–c) one-way ANOVA with Kruskal-Wallis multiple comparisons test. See also the Materials and Methods section.
