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. 2020 Oct 20;10(10):1923. doi: 10.3390/ani10101923

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Research using PDX or PDO that declared an affiliation to the US. Panel A: The number of studies using PDX during the 2014-2019 period showed some fluctuations but overall remained the same during the period. Panel B shows the number of studies using PDX during the period 2014–2019 that received National Institutes of Health (NIH) funding. Note that the number of studies has not increased over the years. Panel C: The proportion of studies using PDX, relative to the total number of using PDX, which were associated with clinical trials, does not show a growing trend. Panel D indicates that research using PDO is on the increase in the US. Panel E shows the number of studies using PDO that received funds from NIH and indicates that most studies using PDO in the US are NIH-funded (or part NIH-funded).