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. 2020 Oct 19;21(20):7729. doi: 10.3390/ijms21207729

Table 2.

Estimation of the 2C/3C relationships of a human standard diet.

Macronutrient Food Intake, g Energy Intake Primary Final Catabolite (mmol/d) 2C/3C Ratio
% kJ/d 1C 2C 3C 4C + 5C
carbohydrate 345 55 5775 3830
lipid 84 30 3150 5400 100
protein 94 15 1575 59 413 93 406
totals 100 10,500 59 5813 4023 406 1.44
5813 4429 1.31

We used standard consensus-recommended diet compositions [168,169] adapted for a 70 kg healthy adult man, assuming his body weight remains without changes (goals expressed by the WHO and EFSA in the references cited above), that is with no accrual neither losses. The intake was adjusted to 10.5 MJ/d (2500 kcal/d or 122 W). Obviously, the distribution in final metabolites for protein may be subjected to wider changes than lipids and carbohydrate, depending on the protein sources of the diet. We have not found published data for population-wide analysis of amino acids for diet protein composition related to complete and time-sustained normal human diets. In order to get an approximation to the sought data, we used instead data for rat cafeteria diet of previous studies from our research group [170,171], on the assumption that the “cafeteria” diet was devised to mimic the usual consumption of food of young humans late in the past century in urban Westernized settings [154]. In the rat cafeteria diet used, the amino acid residues had a mean MW of 126.